Wile E. Coyote runs into some dynamite problems.
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Otis is a mischievous, carefree Holstein cow who lives on a farm where, unbeknownst to humans, the animals are anthropomorphic. He prefers having fun with his best friends: Pip the mouse, Freddy the ferret, Peck the rooster, and Pig the pig - rather than following strict rules and accepting responsibility. This annoys his stern adoptive father Ben, the leader of the farm's community. One evening, Otis convinces Ben to cover his night watch so he can attend a massive party in the barn and impress Daisy, a pregnant cow who recently arrived at the farm with her best friend Bessy as a newcomer. As the animals party, Dag the coyote and his pack attempt to raid the chicken coop. Ben fends them off alone but is fatally wounded and killed. Otis must now learn the value of responsibility when he becomes the leader of his farm home's community.
When The Man in the Yellow Hat befriends Curious George in the jungle, they set off on a non-stop, fun-filled journey through the wonders of the big city toward the warmth of true friendship.
Traumatized? Come to Alfred's Playhouse - the place you can escape to mentally, where only silliness is making forced entry! Alfred, the emotionally-disturbed, Dissociative-Identity-Dis order inflicted dog, sucks you into his fantasy world, created through dissociation to escape from his painful reality. But the Playhouse isn't all that it seems - the fun leads to a penetrating flashback, causing Alfred to spiral further into dillusion - and get a visit from the candyman!
Speedy comes to the aid of a group of mice trying to get the cheese from a factory guarded by Sylvester.
The wasichu scammed all the Indians on the Great Plains. But one day he met Coyote, the master of swindle.
The Easter bunny brings an egg for Tom and Jerry that hatches into the little duckling. He keeps getting into water he shouldn't: the aquarium, water cooler, bathtub, sink, as the boys keep rescuing it. They try to give the duck back to the Easter bunny - no go. They leave it in the pond at the park and think they're home free, until the duckling brings his friends home.
With their freedom on the line, the Looney Tunes seek the help of NBA superstar Michael Jordan to win a basketball game against a team of moronic aliens.
Donald and Goofy are driving across the desert, apparently the Sahara. The car breaks down (out of gas), and they start walking. Before long, they are out of water, and are seeing mirages of soda fountains and icebergs. Fortunately, they find a camel.
Bugs Bunny vs. a famous opera singer at the Hollywood Bowl.
Donald is working in his greenhouse when he notices a bee harvesting nectar (well, actually, it appears to already be honey). Donald tries various approaches to find the hive, which despite the bee's best efforts to throw him off, he eventually discovers in the radiator of an old car. He drains the honey and starts to leave when the bee spots him and mounts an attack. The bee adds a cactus needle to extend his stinger. Donald relents and returns the honey all but one jar, until the bee spots him.
On the night he promised to take Daisy out, Donald Duck discovers he's broke. Desperate for spending money, he gets it in the last place he knows: his three nephews' piggy bank. After their night out, Daisy thanks the 'rich' big spender, which only makes Donald remember how penniless and remorseful he is. What ensues is Donald's guilt (and imagination) taking him on a nerve-wracking ride in the role of a wanted man.
While traveling with his nephews, Donald is disgusted that they are only interested in comics. He stops at the "fountain of youth" and tricks the kids into thinking he is a baby again. However, he gets tangled up with an aggressive mother alligator and her babies, and makes a hurried exit with the nephews.
Peter Cottontail wants to be the #1 chief Easter Bunny, and everyone in April Valley agrees...except for Evil Irontail. Peter must deliver more eggs than this archrival to earn the top spot...and save Easter for children everywhere!
Donald Duck buys a rattletrap used airplane from devious proprietor Ben Buzzard, who tricks the unsuspecting duck into making Ben the beneficiary in case of an accident. Ben then leads Donald on a reckless flight, trying to make the plane crash so that he collect a fortune from Donald's misfortune.
Donald receives a mail order hypnosis kit complete with hypnotic goggles and decides to test it on Pluto. Using the goggles, he convinces Pluto he is a mouse, a turtle, and a chicken. Each "transformation" Pluto undergoes Donald finds extremely funny so he keeps at it until he notices chicken Pluto getting into a fight with a rooster. Donald helps Pluto win the fight by making him think he's a lion but, unfortunately, the goggles break and Donald is chased about by Pluto until he regains his senses after a fall.
Tom and Jerry are in a cabin in the wild west. Jerry's rustling food, so Tom's owner won't let him eat until he's gotten rid of Jerry.
Jerry rescues a bag of puppies from the river. Most of them run away as soon as Jerry releases them, but one stays behind. Jerry tries to get rid of it, but ultimately takes pity and invites the frisky pup inside, where he has to hide it from Tom, who keeps throwing it out.
This was the debut for Wile E. Coyote and the Road Runner. It was also their only cartoon made in the 1940s. It set the template for the series, in which Wile E. Coyote (here given the ersatz Latin name Carnivorous Vulgaris) tries to catch Roadrunner (Accelleratii Incredibus) through many traps, plans and products, although in this first cartoon not all of the products are yet made by the Acme Corporation.
Wile E. Coyote unsuccessfully chases the Road Runner using such contrivances as a rifle, a steel plate, a dynamite stick on an extending metal pulley, a painting of a collapsed bridge (which the Coyote falls into while Road Runner passes right through), and a jet motor.
The wolf, the champion toreador, and Droopy, the challenger, are competing to see who is best in the bullring in the hopes of winning the hand of actress Lina Romay (who appears in a live action shot).